Time-dependent ventilatory response to poikilocapnic hypoxia during light and dark periods and the role of histamine H1 receptors in mice.
نویسندگان
چکیده
We tested the hypothesis that the biphasic ventilatory response to poikilocapnic hypoxia shows circadian variation and contribution of histamine H1 receptors in mice. Initial increases in ventilation were augmented during dark periods. H1 receptors had no major relationship with circadian variation, but affected the declined phase.
منابع مشابه
Hypoxic ventilatory response during light and dark periods and the involvement of histamine H1 receptor in mice.
Ventilation oscillates throughout a day in parallel with oscillations in metabolic rate. Histamine affects ventilation and the balance of the energy metabolism via H1 receptors in the brain. We tested the hypothesis that the ventilatory response to hypoxia varies between light and dark periods and that histamine H1 receptors are required for the circadian variation, using wild-type (WT) and his...
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عنوان ژورنال:
- The journal of physiological sciences : JPS
دوره 58 2 شماره
صفحات -
تاریخ انتشار 2008